Edmonton Alberta Canada

Awards

Congratulations to recent award winners:

Ph.D. student (Suad Rashid) in Leo Spyracopoulos's group was awarded the Dean's Doctoral Award from the Faculty of Medicine and Dentistry in 2020.

Ben Wajda, a former student of Leo Spyracopoulos, was accepted into the M.D. program at the University of Calgary in 2020.

Troy Kervin, BSc student collaborating with Michael Overduin, was given an Office of the Provost and VP (Academic) Summer Student Award in 2020 for research into the structural basis of membrane reader regulation

BSc student Trixie Rae Alda in Michael Overduin's group received a 2020 NSERC Undergraduate Student Research Award for her research into the mechanism of CaMK1D regulation.

Anna Jutla, won a Alberta Innovates Summer Research Studentship in 2020 to continue her research into the discovery of allosteric inhibitors of a phosphotyrosine phosphatase target.

Daniel Gussakovsky received a NSERC CGS-M award to start graduate studies on the identification of RNA-protein complexes central to BC200 regulation of translation in 2020, and is a NSERC USRA holder

Steven Dupas, University of Manitoba received a USRA award for Determination of RNA quadruplex helicase structure/function relationships in 2020.

Mira Brown, University of Manitoba received a USRA award for Characterization of BC200-SRP9/14 complex formation

Jayatee Ray was awarded a NSERC USRA studentship award for "Exploring ligand docking with the apelin receptor through NMR-guided molecular dynamics simulations" and Jeffrey Simmons, also at Dalhousie University, received a NSERC PGS-D award (both in 2020)

Seminars

The Membrane Protein Disease Research Group is holding its annual summer studentsip talks with including by Troy Kervin (Overduin lab) on "Deciphering How Membrane Readers are Controlled" on Aug 20, 2020. Join by Zoom.

Lewis Kay, University of Toronto and Daniella Goldfarb, Weizmann Institute of Science, speak on Emerging Topics in Biomolecular Magnetic Resonance on June 4, 2020 from 8:00 – 9:00am by Zoom

Hans Vogel from the University of Calgary gives a seminar entitled Calcium-binding to L-plastin regulates actin-bundling: target for new antimetastasis drugs? in NANUC on December 9, 2019 from 11am-12pm. Host: Michael Overduin

Frontiers of membrane biology seen by NMR spectroscopy by Michael Overduin on November 22, 2019 3-4pm in MSB 470.

NMR Spectroscopy of Protein Allergens by Dr. Martin Tollinger, University of Innsbruck on September 13, 3:00 PM - 4:00 PM in MSB 4-70.

The 26th Annual E. Garner King Memorial Lecture on June 24 in the Allard Family Lecture Theatre by Lewis E. Kay, University of Toronto on "The Importance of Protein Dynamics in Health and Disease"

Celebration of Brian Sykes' career and honouring of the father of NMR with talks by Malcolm Irving and Gary Shaw from June 13-15.

Meetings

DiscoveryLab meetings are on Nov 13, 2019 and March 11, May 13, June 10 and July 8 in 2020 to help researchers commercialize their research outputs.

NSERC CREATE Training Program in BioActives has been actively developing and expanding the perspective of our trainees on EDI amongst many other professional development activities.

Afsaneh Lavasanifar and coapplicants were awarded a NSERC CREATE Program on "Polymer Nanoparticles for Drug Delivery: from 2020-2022.

SMALP conferences on March 20, June 19 and Sept 18, 2020 to discuss progress on studies of the preparation, structures and interactions of membrane protein complexes and native nanodiscs; organized by Michael Overduin et al.

The Biochemical Society is offering the European SMALP 2021 Conference and Workshop on native nanodiscs for solubilization and analysis of membrane proteins from July 7-9, 2021, with Michael Overduin being the co-Organizer in Canada.

CureCancer TIM bit Tuesday Talks are held throughout the year, and provide an opportunity to hear about cancer research from researchers discovering how to understand, detect and treat cancer more effectively.

Jorg Stetefeld (UManitoba) is organizing a Hydrodynamics-3D Structure workshop in collaboration with the Biophysical Society, and will cover integration of NMR data into a structure/hydrodynamics pipelinep

GRASP Symposium on structural biology at McGill University is usally held each November.

PSFaM Meeting on Protein Structure, Function and Malfunction at the University of Saskatoon from June 20-21, 2019

Ribowest Conference on RNA research in June at the University of Lethbridge.

NMR Spectroscopy Courses

Biochem 675 (UAlberta) covers NMR theory, methods and practice related to characterization of proteins, with subjects including 1D NMR, 2D COSY, TOCSY and NOESY experiments, ligand detection by methods including chemical shift perturbations, saturation transfer difference and filtered NOE's, and double and triple resonance methods for resonance assignment and structure determination. Offered from January to April 2021 by Leo Spyracopoulos, Peter Hwang and Michael Overduin.

Recommended reading includes:

Dieter Ziessow's Understanding Multiple-Pulse Experiments
David Wemmer's Homonuclear Correlated Spectroscopy
Rickey Hicks et. al. on Magnetization Transfer via HOHAHA
Jean Jeener et. al. on Investigation of exchange processes by 2D NMR
Gerhardt Wagner and K. Wüthrich on Sequential resonance assignments
Li, Fan, Brodsky & Baum 2D NMR of collagen triple-helical peptide
Moriz Mayer and Bernd Meyer on Group epitope mapping by STD NMR
Steve Pascal's text NMR Primer on double and triple resonance methods
Lewis Kay on NMR methods for Protein Structure & Dynamics
Anglister, Srivatava and Naider on intermolecular NOE interactions

Protein NMR is also taught by Leo Spyracopoulos in "Methods in Molecular Biophysics", BIOCHEMISTRY 465/565 (UAlberta).

UManitoba offers the following courses with NMR modules:

CHEM 4620 – Biochemistry of Nucleic Acids (includes 1 lecture on basics of biomolecular NMR).

CHEM 4360 – Biochemistry of Proteins (Includes a section on protein structure determination including NMR)

MBIO 7040 - Molecular Biophysics Module (includes a primer on protein NMR)

MBIO 3460 - Membrane Protein Biochemistry (includes a lecture on membrane protein NMR)

NANUC entry

NANUC entry with Heritage Medical Research Centre in back